Cymbalta is a depression and anxiety medication. Here are 13 side effects to know before taking Cymbalta and when to consult your prescriber. Examples of more common side effects of Cymbalta include nausea, dry mouth, constipation, drowsiness, and sexual side effects like decreased libido or delayed orgasm. Serious side effects of. What are the most common side effects of duloxetine? The most common side effects of duloxetine are listed below. Tell your healthcare provider if you have any of these side effects. Cymbalta can cause side effects ranging from nausea to withdrawal symptoms. Here’s an honest look at the risks and who should be cautious about taking it. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Learn about the side effects of Cymbalta (duloxetine), from common to rare, for consumers and healthcare professionals. Common side effects of Cymbalta include nausea, dry mouth, constipation, diarrhea, fatigue, difficulty sleeping, and dizziness, and sexual dysfunction. Consult your doctor before taking Cymbalta if pregnant or breastfeeding. Cymbalta is a prescription drug used for certain mental health conditions and certain types of pain. Learn about its side effects and how you can manage them. Similar to other drugs, Cymbalta may cause side effects (also called adverse effects). Read below for information about possible side effects, including common, mild, and serious ones. Mild side effects of Cymbalta include drowsiness, nausea, and sexual side effects like low libido. These are usually manageable and may go away on their own with time. Cymbalta may also.